Simultaneous Determination of Carbamazepine and Carbamazepine-10,11-epoxide in Different Biological Matrices by LC-MS/MS

An uncomplicated, sensitive liquid chromatography linked to mass spectrometry (LC/MS) for evaluation of carbamazepine and carbamazepine-10,11-epoxide (its metabolite) in human plasma, human saliva, rat plasma, and rabbit plasma was developed. Analyses were conducted on a Zorbax SB-C18, 100 mm × 3 mm...

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Bibliographic Details
Main Authors: Andonie Dan, Gáll Zsolt, Bosa Paul, Dogaru Maria Titica, Vancea Szende
Format: Article
Language:English
Published: Sciendo 2017-09-01
Series:Journal of Interdisciplinary Medicine
Subjects:
Online Access:https://doi.org/10.1515/jim-2017-0075