Polygenic Risk Score Improves Cataract Prediction in East Asian Population

Polygenic Risk Score Improves Cataract Prediction in East Asian Population

Cataracts, characterized by crystalline lens opacities in human eyes, is the leading cause of blindness globally. Due to its multifactorial complexity, the molecular mechanisms remain poorly understood. Larger cohorts of genome-wide association studies (GWAS) are needed to investigate cataracts’ gen...

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Bibliographic Details
Main Authors: Chih-Chien Hsu, Hao-Kai Chuang, Yu-Jer Hsiao, Yuan-Chi Teng, Pin-Hsuan Chiang, Yu-Jun Wang, Ting-Yi Lin, Ping-Hsing Tsai, Chang-Chi Weng, Tai-Chi Lin, De-Kuang Hwang, Ai-Ru Hsieh
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
cataract
genome-wide association studies
polygenic risk score
Asian population
biobank
retrospective study
Online Access:https://www.mdpi.com/2227-9059/10/8/1920

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https://www.mdpi.com/2227-9059/10/8/1920

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