Therapeutic potential of the MDM2 inhibitor Nutlin-3 in counteracting SARS-CoV-2 infection of the eye through p53 activation

Therapeutic potential of the MDM2 inhibitor Nutlin-3 in counteracting SARS-CoV-2 infection of the eye through p53 activation

Starting from the beginning of the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) global pandemic, most of the published data has concentrated on the respiratory signs and symptoms of Covid-19 infection, underestimating the presence and importance of ocular manifestations, such as conj...

Full description

Bibliographic Details
Main Authors: Giorgio Zauli, Sara AlHilali, Samar Al-Swailem, Paola Secchiero, Rebecca Voltan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Medicine
Subjects:
SARS-CoV-2
p53
Nutlin-3
MDM2 inhibitors
eye
cornea
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.902713/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.902713/full

Similar Items