NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting
Abstract Endothelial cells express neuropilin 1 (NRP1), endoglin (ENG) and vascular endothelial growth factor receptor 2 (VEGFR2), which regulate VEGF-A-mediated vascular development and angiogenesis. However, the link between complex formation among these receptors with VEGF-A-induced signaling and...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-05798-2 |