Toward Pediatric T Lymphoblastic Lymphoma Stratification Based on Minimal Disseminated Disease and NOTCH1/FBXW7 Status

Toward Pediatric T Lymphoblastic Lymphoma Stratification Based on Minimal Disseminated Disease and NOTCH1/FBXW7 Status

While outcome for pediatric T lymphoblastic lymphoma (T-LL) has improved with acute leukemia-type therapy, survival after relapse remains rare. Few prognostic markers have been identified: NOTCH1 and/or FBXW7 (N/F) mutations identify good prognosis T-LL and high-level minimal disseminated disease (M...

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Bibliographic Details
Main Authors: Amélie Trinquand, Adriana Plesa, Chrystelle Abdo, Fabien Subtil, Nathalie Aladjidi, Charlotte Rigaud, Aurore Touzart, Ludovic Lhermitte, Arnaud Petit, Katell Michaux, Charlotte Jung, Catherine Chassagne-Clement, Vahid Asnafi, Yves Bertrand, Nathalie Garnier, Elizabeth Macintyre
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000641

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http://journals.lww.com/10.1097/HS9.0000000000000641

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