Oral Administration of Myelin Oligodendrocyte Glycoprotein Attenuates Experimental Autoimmune Encephalomyelitis through Induction of Th2/Treg Cells and Suppression of Th1/Th17 Immune Responses

Oral Administration of Myelin Oligodendrocyte Glycoprotein Attenuates Experimental Autoimmune Encephalomyelitis through Induction of Th2/Treg Cells and Suppression of Th1/Th17 Immune Responses

Multiple Sclerosis (MS) is a demyelinating autoimmune disorder of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) has been widely used to determine the pathogenesis of the disease and evaluate new treatment strategies for MS. Therefore, we investigated the efficacy...

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Bibliographic Details
Main Authors: Dariush Haghmorad, Bahman Yousefi, Majid Eslami, Ali Rashidy-Pour, Mahdieh Tarahomi, Maryam Jadid Tavaf, Azita Soltanmohammadi, Simin Zargarani, Aleksandr Kamyshnyi, Valentyn Oksenych
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Current Issues in Molecular Biology
Subjects:
Multiple Sclerosis
experimental autoimmune encephalomyelitis
Myelin Oligodendrocyte Glycoprotein
Immunomodulatory mechanisms
Online Access:https://www.mdpi.com/1467-3045/44/11/388

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https://www.mdpi.com/1467-3045/44/11/388

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