Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing

The spontaneous bioelectrical activity of pacemaker cells in sinoatrial node (SAN) triggers the heartbeats. Here, the authors perform single-cell RNA sequencing in the mouse SAN and identify molecular and cellular features of the SAN conserved in rabbit and cynomolgus monkey, identifying a new poten...

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Bibliographic Details
Main Authors: Dandan Liang, Jinfeng Xue, Li Geng, Liping Zhou, Bo Lv, Qiao Zeng, Ke Xiong, Huixing Zhou, Duanyang Xie, Fulei Zhang, Jie Liu, Yi Liu, Li Li, Jian Yang, Zhigang Xue, Yi-Han Chen
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20448-x