Development of Fenofibrate/Randomly Methylated β-Cyclodextrin-Loaded Eudragit<sup>®</sup> RL 100 Nanoparticles for Ocular Delivery

Development of Fenofibrate/Randomly Methylated β-Cyclodextrin-Loaded Eudragit<sup>®</sup> RL 100 Nanoparticles for Ocular Delivery

Fenofibrate (FE) has been shown to markedly reduce the progression of diabetic retinopathy and age-related macular degeneration in clinical trials and animal models. Owing to the limited aqueous solubility of FE, it may hamper ocular bioavailability and result in low efficiency to treat such disease...

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Bibliographic Details
Main Authors: Soe Yadanar Khin, Hay Man Saung Hnin Soe, Chaisak Chansriniyom, Natapol Pornputtapong, Rathapon Asasutjarit, Thorsteinn Loftsson, Phatsawee Jansook
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
cyclodextrin
fenofibrate
complexation
eye drops: nanocarriers
permeation
Online Access:https://www.mdpi.com/1420-3049/27/15/4755

Internet

https://www.mdpi.com/1420-3049/27/15/4755

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