Temperature responses of mutation rate and mutational spectrum in an Escherichia coli strain and the correlation with metabolic rate

Temperature responses of mutation rate and mutational spectrum in an Escherichia coli strain and the correlation with metabolic rate

Abstract Background Temperature is a major determinant of spontaneous mutation, but the precise mode, and the underlying mechanisms, of the temperature influences remain less clear. Here we used a mutation accumulation approach combined with whole-genome sequencing to investigate the temperature dep...

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Bibliographic Details
Main Authors: Xiao-Lin Chu, Bo-Wen Zhang, Quan-Guo Zhang, Bi-Ru Zhu, Kui Lin, Da-Yong Zhang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Evolutionary Biology
Subjects:
Evolutionary speed hypothesis
Molecular evolution
Mutation accumulation
Mutation rate
Mutational spectrum
Oxidative DNA damage
Online Access:http://link.springer.com/article/10.1186/s12862-018-1252-8

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http://link.springer.com/article/10.1186/s12862-018-1252-8

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