SEMplMe: a tool for integrating DNA methylation effects in transcription factor binding affinity predictions
Abstract Motivation Aberrant DNA methylation in transcription factor binding sites has been shown to lead to anomalous gene regulation that is strongly associated with human disease. However, the majority of methylation-sensitive positions within transcription factor binding sites remain unknown. He...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-08-01
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| Series: | BMC Bioinformatics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12859-022-04865-x |