Diverse Roles of SIRT1 in Cancer Biology and Lipid Metabolism
SIRT1, an NAD+-dependent deacetylase, has been described in the literature as a major player in the regulation of cellular stress responses. Its expression has been shown to be altered in cancer cells, and it targets both histone and non-histone proteins for deacetylation and thereby alters metaboli...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-01-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/16/1/950 |