Resveratrol Ameliorates Microcystin-LR-Induced Testis Germ Cell Apoptosis in Rats via SIRT1 Signaling Pathway Activation

Resveratrol Ameliorates Microcystin-LR-Induced Testis Germ Cell Apoptosis in Rats via SIRT1 Signaling Pathway Activation

Microcystin-leucine arginine (MC-LR), a cyclic heptapeptide produced by cyanobacteria, is a strong reproductive toxin. Studies performed in rat Sertoli cells and Chinese hamster ovary cells have demonstrated typical apoptosis after MC-LR exposure. However, little is known on how to protect against t...

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Bibliographic Details
Main Authors: Haohao Liu, Shenshen Zhang, Chuanrui Liu, Jinxia Wu, Yueqin Wang, Le Yuan, Xingde Du, Rui Wang, Phelisters Wegesa Marwa, Donggang Zhuang, Xuemin Cheng, Huizhen Zhang
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Toxins
Subjects:
apoptosis
microcystin-LR (MC-LR)
reproductive toxicity
resveratrol
sirtuin 1 (SIRT1)
Online Access:http://www.mdpi.com/2072-6651/10/6/235

Internet

http://www.mdpi.com/2072-6651/10/6/235

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