Emerging Epigenetic and Posttranslational Mechanisms Controlling Resistance to Glucocorticoids in Acute Lymphoblastic Leukemia

Glucocorticoids are extensively used for the treatment of acute lymphoblastic leukemia as they pressure cancer cells to undergo apoptosis. Nevertheless, glucocorticoid partners, modifications, and mechanisms of action are hitherto poorly characterized. This hampers our understanding of therapy resis...

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Bibliographic Details
Main Authors: Cristina Borin, Tim Pieters, Valentina Serafin, Panagiotis Ntziachristos
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000916