Impact of Peptidoglycan Recycling Blockade and Expression of Horizontally Acquired β-Lactamases on Pseudomonas aeruginosa Virulence

Impact of Peptidoglycan Recycling Blockade and Expression of Horizontally Acquired β-Lactamases on Pseudomonas aeruginosa Virulence

ABSTRACT In the current scenario of antibiotic resistance magnification, new weapons against top nosocomial pathogens like Pseudomonas aeruginosa are urgently needed. The interplay between β-lactam resistance and virulence is considered a promising source of targets to be attacked by antivirulence t...

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Bibliographic Details
Main Authors: Isabel M. Barceló, Gabriel Torrens, María Escobar-Salom, Elena Jordana-Lluch, María Magdalena Capó-Bauzá, Carlos Ramón-Pallín, Daniel García-Cuaresma, Pablo A. Fraile-Ribot, Xavier Mulet, Antonio Oliver, Carlos Juan
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas aeruginosa
peptidoglycan recycling
AmpG
NagZ
AmpC cephalosporinase
horizontally acquired β-lactamases
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02019-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.02019-21

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