Identification of functional pathways and molecular signatures in neuroendocrine neoplasms by multi-omics analysis

Identification of functional pathways and molecular signatures in neuroendocrine neoplasms by multi-omics analysis

Abstract Background Neuroendocrine neoplasms (NENs) represent a heterogeneous class of rare tumors with increasing incidence. They are characterized by the ability to secrete peptide hormones and biogenic amines but other reliable biomarkers are lacking, making diagnosis and identification of the pr...

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Main Authors: Viola Melone, Annamaria Salvati, Domenico Palumbo, Giorgio Giurato, Giovanni Nassa, Francesca Rizzo, Luigi Palo, Alessandro Giordano, Mariarosaria Incoronato, Mario Vitale, Caterina Mian, Immacolata Di Biase, Stefano Cristiano, Viviana Narciso, Monica Cantile, Annabella Di Mauro, Fabiana Tatangelo, Salvatore Tafuto, Roberta Modica, Claudia Pivonello, Marco Salvatore, Annamaria Colao, Alessandro Weisz, Roberta Tarallo
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Translational Medicine
Subjects:
Neuroendocrine neoplasms
Molecular signatures
ATM signaling
Circulating biomarkers
Online Access:https://doi.org/10.1186/s12967-022-03511-7

Internet

https://doi.org/10.1186/s12967-022-03511-7

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