Distinct immune signature predicts progression of vestibular schwannoma and unveils a possible viral etiology

Distinct immune signature predicts progression of vestibular schwannoma and unveils a possible viral etiology

Abstract Background The management of sub-totally resected sporadic vestibular schwannoma (VS) may include observation, re-resection or irradiation. Identifying the optimal choice can be difficult due to the disease’s variable progression rate. We aimed to define an immune signature and associated t...

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Bibliographic Details
Main Authors: Moran Amit, Tongxin Xie, Frederico O. Gleber-Netto, Patrick J. Hunt, Gautam U. Mehta, Diana Bell, Deborah A. Silverman, Ismail Yaman, Yi Ye, Jared K. Burks, Gregory N. Fuller, Paul W. Gidley, Marc-Elie Nader, Shaan M. Raza, Franco DeMonte
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Vestibular schwannoma
Skull base
Surgery
Immune
Viral
Progression
Online Access:https://doi.org/10.1186/s13046-022-02473-4

Internet

https://doi.org/10.1186/s13046-022-02473-4

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