Identification of Calpain Substrates by ORF Phage Display

Substrate identification is the key to defining molecular pathways or cellular processes regulated by proteases. Although phage display with random peptide libraries has been used to analyze substrate specificity of proteases, it is difficult to deduce endogenous substrates from mapped peptide motif...

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Bibliographic Details
Main Authors: Wei Li, Gabriela Alvarado, Nora B. Caberoy
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/2/1739/