Monocytes engineered with iSNAP inhibit human B‐lymphoma progression

Monocytes engineered with iSNAP inhibit human B‐lymphoma progression

Abstract Monocytes are important regulators for the maintenance of homeostasis in innate and adaptive immune system and have been reported to play important role in cancer progression. CD47‐SIRPα recognition is a coinhibitory immune signal to inhibit phagocytosis in monocytes and macrophages and has...

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Bibliographic Details
Main Authors: Haohsiang Wu, Siamak Amirfakhri, Hsin‐Hung Lin, Hannah Hollandsworth, Filemoni Filemoni, Yahan Liu, Yiqian Wu, Julie Y. S. Li, Hongquan Xu, Shu Chien, Michael Bouvet, Yingxiao Wang
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Bioengineering & Translational Medicine
Subjects:
cancer immunotherapy
CD47
Don't eat me signal
engineering monocytes
macrophage polarization
Online Access:https://doi.org/10.1002/btm2.10285

Internet

https://doi.org/10.1002/btm2.10285

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