Glucocorticoids selectively affect the memory T cell response to SARS-Cov2 spike in vaccinated and post-infected patients with systemic lupus erythematosus

Glucocorticoids selectively affect the memory T cell response to SARS-Cov2 spike in vaccinated and post-infected patients with systemic lupus erythematosus

Immune response to vaccines and pathogens remains unclear in patients with systemic lupus erythematosus (SLE). To investigate this, a single-center retrospective study was conducted with 47 SLE patients vaccinated against COVID-19, including 13 who subsequently developed an asymptomatic/mild disease...

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Bibliographic Details
Main Authors: Yves Renaudineau, Chloé Bost, Florence Abravanel, Jacques Izopet, Antoine Blancher, Nicolas Congy, Emmanuel Treiner, Laurent Sailler
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Translational Autoimmunity
Subjects:
Systemic lupus erythematosus
Spike
Nucleocapsid
COVID-19
Antibody
Interferon gamma release assay
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909023000138

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http://www.sciencedirect.com/science/article/pii/S2589909023000138

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