IGF2 reduces meiotic defects in oocytes from obese mice and improves embryonic developmental competency

IGF2 reduces meiotic defects in oocytes from obese mice and improves embryonic developmental competency

Abstract Background Maternal obesity is a global issue that has devastating effects across the reproductive spectrum such as meiotic defects in oocytes, consequently worsening pregnancy outcomes. Different studies have shown that such types of meiotic defects originated from the oocytes of obese mot...

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Bibliographic Details
Main Authors: Yanling Wan, Tahir Muhammad, Tao Huang, Yue Lv, Qianqian Sha, Shuang Yang, Gang Lu, Wai-yee Chan, Jinlong Ma, Hongbin Liu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Reproductive Biology and Endocrinology
Subjects:
Maternal obesity
Oocyte quality
IGF2
Meiotic defects
Online Access:https://doi.org/10.1186/s12958-022-00972-9

Internet

https://doi.org/10.1186/s12958-022-00972-9

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