The Importance of Pore-Forming Toxins in Multiple Organ Injury and Dysfunction

The Importance of Pore-Forming Toxins in Multiple Organ Injury and Dysfunction

Background: Multiple organ injury and dysfunction often occurs in acute critical illness and adversely affects survival. However, in patients who survive, organ function usually recovers without permanent damage. It is, therefore, likely that there are reversible mechanisms, but this is poorly under...

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Bibliographic Details
Main Authors: Simon T. Abrams, Lijun Wang, Jun Yong, Qian Yu, Min Du, Yasir Alhamdi, Zhenxing Cheng, Caroline Dart, Steven Lane, Weiping Yu, Cheng-Hock Toh, Guozheng Wang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
pore-forming toxin
cell membrane integrity
extracellular histones
pneumolysin
sepsis
multiple organ injury
Online Access:https://www.mdpi.com/2227-9059/10/12/3256

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https://www.mdpi.com/2227-9059/10/12/3256

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