Novel approach for reconstruction of the three-dimensional biliary system in decellularized liver scaffold using hepatocyte progenitors.

Reconstruction of the biliary system is indispensable for the regeneration of transplantable liver grafts. Here, we report the establishment of the first continuous three-dimensional biliary system scaffold for bile acid excretion using a novel method. We confirmed the preservation of the liver-deri...

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Bibliographic Details
Main Authors: Kazuya Hirukawa, Hiroshi Yagi, Kohei Kuroda, Masafumi Watanabe, Kotaro Nishi, Shogo Nagata, Yuta Abe, Minoru Kitago, Shungo Adachi, Ryo Sudo, Yuko Kitagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0297285&type=printable