Activation of basolateral amygdala to anterior cingulate cortex circuit alleviates MK-801 induced social and cognitive deficits of schizophrenia

Activation of basolateral amygdala to anterior cingulate cortex circuit alleviates MK-801 induced social and cognitive deficits of schizophrenia

IntroductionSchizophrenia is a severe psychiatric disorder with a high prevalence worldwide, however, its pathogenesis remains poorly understood.Methods and resultsIn this study, we used the non-competitive NMDA receptor antagonist MK-801 to induce schizophrenia-like behaviors and confirmed that mic...

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Bibliographic Details
Main Authors: Xin Huang, Yaohao Li, Haiying Liu, Jinwei Xu, Zehua Tan, Haoyang Dong, Biqing Tian, Shengxi Wu, Wenting Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
MK-801
schizophrenia
anterior cingulate cortex (ACC)
basolateral amygdala (BLA)
cognitive deficits
social deficits
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.1070015/full

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https://www.frontiersin.org/articles/10.3389/fncel.2022.1070015/full

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