How many sites should an orthopedic trauma prospective multicenter trial have? A marginal analysis of the Major Extremity Trauma Research Consortium completed trials

How many sites should an orthopedic trauma prospective multicenter trial have? A marginal analysis of the Major Extremity Trauma Research Consortium completed trials

Abstract Background Multicenter trials in orthopedic trauma are costly, yet crucial to advance the science behind clinical care. The number of sites is a key cost determinant. Each site has a fixed overhead cost, so more sites cost more to the study. However, more sites can reduce total costs by sho...

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Bibliographic Details
Main Authors: Lauren Allen, Robert V. O’Toole, Michael J. Bosse, William T. Obremskey, Kristin R. Archer, Lisa K. Cannada, Jaimie Shores, Lisa M. Reider, Katherine P. Frey, Anthony R. Carlini, Elena D. Staguhn, Renan C. Castillo
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Trials
Subjects:
Multicenter trials
Research operations
Financial management
Online Access:https://doi.org/10.1186/s13063-024-07917-0

Internet

https://doi.org/10.1186/s13063-024-07917-0

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