Impact of Sr2+ and hypoxia on 3D triple cultures of primary human osteoblasts, osteocytes and osteoclasts

An in vitro bone triple culture involving human primary osteoblasts, osteocytes and osteoclasts enables the investigation of bone healing factors, drugs or biomaterials in a model system for native bone tissue. The present study analyses the impact of Sr2+ as well as hypoxic cultivation (5% O2 conte...

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Bibliographic Details
Main Authors: Katharina Wirsig, David Kilian, Max von Witzleben, Michael Gelinsky, Anne Bernhardt
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:European Journal of Cell Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933522000590