The Role of MeCP2 in Regulating Synaptic Plasticity in the Context of Stress and Depression

Methyl-CpG-binding protein 2 (MeCP2) is a transcriptional regulator that is highly abundant in the brain. It binds to methylated genomic DNA to regulate a range of physiological functions implicated in neuronal development and adult synaptic plasticity. MeCP2 has mainly been studied for its role in...

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Bibliographic Details
Main Authors: Carla L. Sánchez-Lafuente, Lisa E. Kalynchuk, Hector J. Caruncho, Juan Ausió
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/4/748