Interleukin-1β mediates GDNF up-regulation upon dopaminergic injury in ventral midbrain cell cultures

Interleukin-1β mediates GDNF up-regulation upon dopaminergic injury in ventral midbrain cell cultures

We recently proposed the involvement of diffusible modulators in signalling astrocytes to increase glial cell line-derived neurotrophic factor (GDNF) expression after selective dopaminergic injury by H2O2 or l-DOPA. Here we report that interleukin-1β (IL-1β) is involved in this crosstalk between inj...

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Bibliographic Details
Main Authors: Ana Saavedra, Graça Baltazar, Emília P. Duarte
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Neurobiology of Disease
Subjects:
Astrocytes
Crosstalk
Dopaminergic neurons
GDNF
IL-1β
Injury
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106002142

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http://www.sciencedirect.com/science/article/pii/S0969996106002142

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