Induced pluripotent stem cell therapy ameliorates hyperoxia-augmented ventilator-induced lung injury through suppressing the Src pathway.

BACKGROUND: High tidal volume (VT) mechanical ventilation (MV) can induce the recruitment of neutrophils, release of inflammatory cytokines and free radicals, and disruption of alveolar epithelial and endothelial barriers. It is proposed to be the triggering factor that initiates ventilator-induced...

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Bibliographic Details
Main Authors: Yung-Yang Liu, Li-Fu Li, Jui-Ying Fu, Kuo-Chin Kao, Chung-Chi Huang, Yueh Chien, Yi-Wen Liao, Shih-Hwa Chiou, Yuh-Lih Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4195701?pdf=render