Efflux pumps mediate changes to fundamental bacterial physiology via membrane potential

Efflux pumps mediate changes to fundamental bacterial physiology via membrane potential

ABSTRACT Efflux pumps are well known to be an important mechanism for removing noxious substances such as antibiotics from bacteria. Given that many antibiotics function by accumulating inside bacteria, efflux pumps contribute to resistance. Efflux pump inactivation is a potential strategy to combat...

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Bibliographic Details
Main Authors: Emily E. Whittle, Oluwatosin Orababa, Alexander Osgerby, Pauline Siasat, Sarah J. Element, Jessica M. A. Blair, Tim W. Overton
Format: Article
Language:English
Published: American Society for Microbiology 2024-10-01
Series:mBio
Subjects:
hyperpolarization
RND efflux pump
AcrAB-TolC
ArcBA
redox state
energy metabolism
Online Access:https://journals.asm.org/doi/10.1128/mbio.02370-24

Internet

https://journals.asm.org/doi/10.1128/mbio.02370-24

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