Human PIEZO1 Ion Channel Functions as a Split Protein.

PIEZO1 is a mechanosensitive eukaryotic cation-selective channel that rapidly inactivates in a voltage-dependent manner. We previously showed that a fluorescent protein could be encoded within the hPIEZO1 sequence without loss of function. In this work, we split the channel into two at this site and...

Full description

Bibliographic Details
Main Authors: Chilman Bae, Thomas M Suchyna, Lynn Ziegler, Frederick Sachs, Philip A Gottlieb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4786117?pdf=render