Regional fat depot masses are influenced by protein-coding gene variants.

Waist-to-hip ratio (WHR) is a prominent cardiometabolic risk factor that increases cardio-metabolic disease risk independently of BMI and for which multiple genetic loci have been identified. However, WHR is a relatively crude proxy for fat distribution and it does not capture all variation in fat d...

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Bibliographic Details
Main Authors: Matt J Neville, Laura B L Wittemans, Katherine E Pinnick, Marijana Todorčević, Risto Kaksonen, Kirsi H Pietiläinen, Jian'an Luan, Robert A Scott, Nicholas J Wareham, Claudia Langenberg, Fredrik Karpe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217644