18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells

18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells

<p><b>Objective:</b> To investigate the effects of 18&#945;-glycyrrhetinic acid (18&#945;-GA) on the expression of type I and III collagen in human and rat hepatic stellate cells (HSC) and to explore the role of TGF-&#946;1/Smad signaling pathway involved.</p><...

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Bibliographic Details
Main Author: Lei Zong, Ying Qu, Ming-yi Xu, Yu-wei Dong, Lun-gen Lu
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v09p0370.htm

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http://www.medsci.org/v09p0370.htm

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