Dopamine Neuron Diversity: Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing

Dopamine Neuron Diversity: Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing

Human midbrain dopamine (DA) neurons are a heterogeneous group of cells that share a common neurotransmitter phenotype and are in close anatomical proximity but display different functions, sensitivity to degeneration, and axonal innervation targets. The A9 DA neuron subtype controls motor function...

Full description

Bibliographic Details
Main Authors: Alessandro Fiorenzano, Edoardo Sozzi, Malin Parmar, Petter Storm
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
human pluripotent stem cells
dopamine neuron differentiation
Parkinson’s disease
human brain organoids
cell transplantation
single cell RNA sequencing
Online Access:https://www.mdpi.com/2073-4409/10/6/1366

Internet

https://www.mdpi.com/2073-4409/10/6/1366

Similar Items