The genetic and dietary landscape of the muscle insulin signalling network

The genetic and dietary landscape of the muscle insulin signalling network

Metabolic disease is caused by a combination of genetic and environmental factors, yet few studies have examined how these factors influence signal transduction, a key mediator of metabolism. Using mass spectrometry-based phosphoproteomics, we quantified 23,126 phosphosites in skeletal muscle of fiv...

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Bibliographic Details
Main Authors: Julian van Gerwen, Stewart WC Masson, Harry B Cutler, Alexis Diaz Vegas, Meg Potter, Jacqueline Stöckli, Søren Madsen, Marin E Nelson, Sean J Humphrey, David E James
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-02-01
Series:eLife
Subjects:
phosphoproteomics
mass spectrometry
signalling
metabolism
genetics
insulin resistance
Online Access:https://elifesciences.org/articles/89212

Internet

https://elifesciences.org/articles/89212

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