High Throughput Analyses of Budding Yeast ARSs Reveal New DNA Elements Capable of Conferring Centromere-Independent Plasmid Propagation

High Throughput Analyses of Budding Yeast ARSs Reveal New DNA Elements Capable of Conferring Centromere-Independent Plasmid Propagation

The ability of plasmids to propagate in Saccharomyces cerevisiae has been instrumental in defining eukaryotic chromosomal control elements. Stable propagation demands both plasmid replication, which requires a chromosomal replication origin (i.e., an ARS), and plasmid distribution to dividing cells,...

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Bibliographic Details
Main Authors: Timothy Hoggard, Ivan Liachko, Cassaundra Burt, Troy Meikle, Katherine Jiang, Gheorghe Craciun, Maitreya J. Dunham, Catherine A. Fox
Format: Article
Language:English
Published: Oxford University Press 2016-04-01
Series:G3: Genes, Genomes, Genetics
Subjects:
silencers
plasmid partitioning
DNA replication origins
deep mutational scanning
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.027904

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.027904

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