Effect of Chondroitinase ABC Enzyme on Glial Fibrillary Acidic Protein, Chondroitin Sulfated Proteoglycans and Chondroitin 4-Sulfate Levels in an Animal Model of Spinal Cord Injury
Background: Following spinal cord injury, reactive astrocytes upregulate chondroitin sulfate proteoglycans (CSPGs) which act as a barrier to neuronal repair and regeneration. Therefore, enzymatic digestion of CSPGs by chondroitinase ABC (cABC) is a key strategy in the treatment of spinal cord injury...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kerman University of Medical Sciences
2017-07-01
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| Series: | Journal of Kerman University of Medical Sciences |
| Subjects: | |
| Online Access: | https://jkmu.kmu.ac.ir/article_53925_eee85a1648ed72a6e68d1efc1a555980.pdf |