Activation of Nrf2 antioxidant signaling alleviates gout arthritis pain and inflammation

Activation of Nrf2 antioxidant signaling alleviates gout arthritis pain and inflammation

Excessive deposition of monosodium urate (MSU) crystal in the joint results in gout arthritis, which triggers severe pain and affects life quality. Oxidative stress is a pivotal mechanism that contributes to etiology of gout pain and inflammation. Here we investigated whether activating Nrf2, which...

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Bibliographic Details
Main Authors: Danyi Zeng, Chengyu Yin, Huina Wei, Yuanyuan Li, Yunqin Yang, Huimin Nie, Yushuang Pan, Ruoyao Xu, Yan Tai, Junying Du, Jinggen Liu, Ping Wang, Boyu Liu, Boyi Liu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Gout
Nrf2
ROS
Pain
TRPV1
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223017559

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223017559

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