Dissecting the conformation of glycans and their interactions with proteins

Dissecting the conformation of glycans and their interactions with proteins

Abstract The use of in silico strategies to develop the structural basis for a rational optimization of glycan-protein interactions remains a great challenge. This problem derives, in part, from the lack of technologies to quantitatively and qualitatively assess the complex assembling between a glyc...

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Bibliographic Details
Main Authors: Sheng-Hung Wang, Tsai-Jung Wu, Chien-Wei Lee, John Yu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Biomedical Science
Subjects:
Glycan
Glycosphingolipid
Conformational changes
SPARC
Globo H Ceramide
Molecular modeling
Online Access:http://link.springer.com/article/10.1186/s12929-020-00684-5

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http://link.springer.com/article/10.1186/s12929-020-00684-5

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