Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation

Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation

Summary: Long intergenic noncoding RNAs (lincRNAs) are critical regulators involved in diverse biological processes. However, the roles and related mechanisms of lincRNAs in axon development are largely unknown. Here we report an axon-enriched lincRNA regulating axon elongation, referred to as ALAE....

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Bibliographic Details
Main Authors: Manyi Wei, Jiansong Huang, Guo-Wei Li, Bowen Jiang, Hong Cheng, Xiaoyan Liu, Xingyu Jiang, Xu Zhang, Li Yang, Lan Bao, Bin Wang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports
Subjects:
axon-enriched lincRNA
axon elongation
KHSRP
GAP43
local translation
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721003697

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http://www.sciencedirect.com/science/article/pii/S2211124721003697

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