Induction of tyrosine aminotransferase in mice is inhibited by activated metabolites of ortho- aminoazotoluene

Induction of tyrosine aminotransferase in mice is inhibited by activated metabolites of ortho- aminoazotoluene

Aminoazo dyes and other hepatocarcinogenic substances inhibit glucocorticoid-mediated induction of adaptive enzymes, including tyrosine aminotransferase (TAT), in mouse and rat liver. There is a specific relationship between the effect of a carcinogen on TAT induction and its liver carcinogenicity i...

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Bibliographic Details
Main Authors: V. I. Kaledin, S. I. Ilnitskaya, N. A. Popova, O. A. Koval, I. A. Pyshnaya, L. F. Gulyaeva
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2015-07-01
Series:Вавиловский журнал генетики и селекции
Subjects:
mice
ortho-aminoazotoluene
tyrosine aminotransferase
enzyme induction and inhibition
Online Access:https://vavilov.elpub.ru/jour/article/view/356

Internet

https://vavilov.elpub.ru/jour/article/view/356

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