Pharmacogenetic Variants Associated with Fluoxetine Pharmacokinetics from a Bioequivalence Study in Healthy Subjects

Fluoxetine is one of the most prescribed antidepressants, yet it still faces challenges due to high intersubject variability in patient response. Mainly metabolized by the highly polymorphic gene <i>CYP2D6</i>, important differences in plasma concentrations after the same doses are found...

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Bibliographic Details
Main Authors: Carlos Alejandro Díaz-Tufinio, José Antonio Palma-Aguirre, Vanessa Gonzalez-Covarrubias
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/13/9/1352