Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension

Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) can be found in patients suffering from a loss-of-function mutation of the gene encoding for the activin receptor-like kinase 1 (ALK-1), a bone morphogenetic protein (BMP) type 1 receptor. Interestingly, ALK-1 mutations also lead to hereditary hemorrhagic telang...

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Bibliographic Details
Main Authors: N Sommer, F Droege, KE Gamen, U Geisthoff, H Gall, K Tello, MJ Richter, LM Deubner, R Schmiedel, M Hecker, E Spiekerkoetter, K Wirsching, W Seeger, HA Ghofrani, S Pullamsetti
Format: Article
Language:English
Published: Wiley 2018-11-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894018805406

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https://doi.org/10.1177/2045894018805406

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