Spleen‐targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma

Abstract Neoantigens are emerging as attractive targets to develop personalized cancer vaccines, but their immunization efficacy is severely hampered by their restricted accessibility to lymphoid tissues where immune responses are initiated. Leveraging the capability of red blood cells (RBCs) to cap...

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Bibliographic Details
Main Authors: Ming Wu, Zijin Luo, Zhixiong Cai, Qianqian Mao, Zhenli Li, Hao Li, Cao Zhang, Yuting Zhang, Aoxue Zhong, Liming Wu, Xiaolong Liu
Format: Article
Language:English
Published: Springer Nature 2023-10-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.202216836