PAFR/Stat3 axis maintains the symbiotic ecosystem between tumor and stroma to facilitate tumor malignancy

Stroma surrounding the tumor cells plays crucial roles for tumor progression. However, little is known about the factors that maintain the symbiosis between stroma and tumor cells. In this study, we found that the transcriptional regulator-signal transducer and activator of transcription 3 (Stat3) w...

Full description

Bibliographic Details
Main Authors: Di Zhao, Jing Zhang, Lingyuan Zhang, Qingnan Wu, Yan Wang, Weimin Zhang, Yuanfan Xiao, Jie Chen, Qimin Zhan
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522003653