Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish.

Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish.

Reporter-based assays underlie many high-throughput screening (HTS) platforms, but most are limited to in vitro applications. Here, we report a simple whole-organism HTS method for quantifying changes in reporter intensity in individual zebrafish over time termed, Automated Reporter Quantification i...

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Bibliographic Details
Main Authors: Steven L Walker, Junko Ariga, Jonathan R Mathias, Veena Coothankandaswamy, Xiayang Xie, Martin Distel, Reinhard W Köster, Michael J Parsons, Kapil N Bhalla, Meera T Saxena, Jeff S Mumm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22238673/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22238673/?tool=EBI

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