The NF-κB RelA transcription factor is not required for CD8+ T-cell function in acute viral infection and cancer

The NF-κB RelA transcription factor is not required for CD8+ T-cell function in acute viral infection and cancer

CD8+ T cells are critical mediators of pathogen clearance and anti-tumor immunity. Although signaling pathways leading to the activation of NF-κB transcription factors have crucial functions in the regulation of immune responses, the CD8+ T cell-autonomous roles of the different NF-κB subunits, are...

Full description

Bibliographic Details
Main Authors: Allison Voisin, Maud Plaschka, Marlène Perrin-Niquet, Julie Twardowski, Insaf Boutemine, Baptiste Eluard, Guilhem Lalle, Pierre Stéphan, Khaled Bouherrou, Laurie Tonon, Roxane Pommier, Anthony Ferrari, Ulf Klein, Mélanie Wencker, Véronique Baud, Philippe A. Cassier, Yenkel Grinberg-Bleyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
CD8 + T cells
NF-KappaB
cancer
immunotherapy
LCMV
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1379777/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1379777/full

Similar Items