p53 Affects Zeb1 Interactome of Breast Cancer Stem Cells

p53 Affects Zeb1 Interactome of Breast Cancer Stem Cells

P53 is a critical tumor suppressor that protects the integrity of genome and prevents cells from malignant transformation, including metastases. One of the driving forces behind the onset of metastases is the epithelial to mesenchymal transition (EMT) program. Zeb1 is one of the key transcription fa...

Full description

Bibliographic Details
Main Authors: Sergey E. Parfenyev, Sergey V. Shabelnikov, Elena N. Tolkunova, Nickolai A. Barlev, Alexey G. Mittenberg
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
cancer stem cells
epithelial-to-mesenchymal transition (EMT)
metastasis
p53
Zeb1
Online Access:https://www.mdpi.com/1422-0067/24/12/9806

Internet

https://www.mdpi.com/1422-0067/24/12/9806

Similar Items