Electron-Beam Irradiated Recombinant Human Collagen-Phosphorylcholine Corneal Implants Retain Pro-Regeneration Capacity

Electron-Beam Irradiated Recombinant Human Collagen-Phosphorylcholine Corneal Implants Retain Pro-Regeneration Capacity

Sterilization of biodegradable, collagen-based implants is challenging as irradiation sterilization methods can alter their mechanical properties. Electron beam (EB) irradiation is a terminal sterilization method that has been used for biologically-derived implants. Here, recombinant human collagen...

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Bibliographic Details
Main Authors: Fiona C. Simpson, Mohammed Mirazul Islam, Oleksiy Buznyk, Elle Edin, Marc Groleau, Monika Kozak-Ljunggren, Federica M. Magrelli, Dina B. AbuSamra, Pablo Argüeso, James Chodosh, Aneta Liszka, Per Fagerholm, May Griffith
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
collagen
implant
E-beam
irradiation
rabbits
cornea
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.883977/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.883977/full

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