Correlated miR-mRNA expression signatures of mouse hematopoietic stem and progenitor cell subsets predict "Stemness" and "Myeloid" interaction networks.

Several individual miRNAs (miRs) have been implicated as potent regulators of important processes during normal and malignant hematopoiesis. In addition, many miRs have been shown to fine-tune intricate molecular networks, in concert with other regulatory elements. In order to study hematopoietic ne...

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Bibliographic Details
Main Authors: Diane Heiser, Yee Sun Tan, Ian Kaplan, Brian Godsey, Sebastien Morisot, Wen-Chih Cheng, Donald Small, Curt I Civin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3991639?pdf=render