Structurally conserved C-RFa revealed prolactin releasing activity in vitro and gene expression changes in pituitary of seasonally acclimatized carp

Here we show the cloning and characterization of a novel homolog of prepro C-RFa cDNA from Cyprinus carpió. The deduced preprohormone precursor of 115 amino acids leads to a mature bioactive peptide of 20 amino acids with identical sequence to other teleost C-RFa. Modeling of the mature C-RFa peptid...

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Bibliographic Details
Main Authors: Alex Romero, Rodrigo Montefusco-Siegmund, Guillermo Valenzuela, Gudrun Kausel, Marc Muller, Sebastian Brauchi, Jaime Figueroa
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000200011